Your DNA Is Going On-Chain 🧬

Thank God It’s Fridayyy—and Day 2 of our revamping the newsletter to serve you better.

In Today’s Edition

🌕Market Watch
🌕Sei’s Desci Bet
🌕Grayscale’s Market Report 
🌕AI Agents Evolution

Like we said yesterday, we can’t grow without you, so let us know your thoughts on today’s edition.

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To today’s stories ===>>

Market Watch 🔍

Markets are navigating a tightrope as crypto investors weigh macroeconomic uncertainty against pockets of altcoin surges. 

The crypto market slumped 4% yesterday on Trump’s tariffs, with Bitcoin falling below $85k. The coin has since ranged between $87k and $85k 

$SUI led the winners' camp with a 7.1% rally, outpacing AAVE’s 3.6% gains. Meanwhile, both Dogecoin and XRP stumbled, each down over 5%, as traders de-risked ahead of a high-stakes U.S. inflation print. 

“Narratives over technicals” is how some traders escape the grueling taste of crypto research. 

They may have more points now as Toncoin surged 10% on Elon Musk’s Grok AI integration into Telegram, while SUI's ETF aspirations fueled fresh institutional optimism. 

But whether these gains hold amid broader economic jitters remains the real test.

We Felt The Pain Too - Grayscale

According to Grayscale’s latest research, it wasn’t just your portfolio feeling the pain of crypto’s stumble in 2025. 

The sector’s price index tumbled 18% in Q1, led, of course, by the sector where token nosedive for fun: memecoins.

Solana, a favorite haunt for meme traders, saw its active users wane, but still raked in nearly half of the smart contract segment’s total fees—$390 million.

Looking ahead, Grayscale is pivoting its focus toward RWAs and DePINs, betting on projects like Maple and Geodnet.  

Meanwhile, Bitcoin’s network activity remains robust, with 11 million monthly active on-chain users, reinforcing its role as a store of value rather than a medium of exchange. 

The key takeaway? While memes may be losing their grip, the market is primed for new narratives—RWAs, DeFi, and AI-infused crypto solutions could take center stage in Q2.

What’s your pick?

Sei Wants Your Gene On-Chain

“Hey. you’ve got great genes.”

“Thanks; you check them out on Etherscan.”

This is the future Sei wants to create with an unlikely acquisition of a struggling genetics startup.

Sei Foundation is setting its sights on the bankrupt genetic testing company 23andMe, which has struggled to turn a profit since going public.

For Sei, it’s a pitch for a bold new experiment in decentralized science (DeSci).

Calling the move its "boldest DeSci bet yet," Sei wants to integrate 23andMe's 15 million user genetic records onto its blockchain, allowing individuals to own, encrypt, and monetize their DNA data. 

The nonprofit foundation argues that genomic data security is a national security concern, particularly as 23andMe faces mounting financial distress.

If successful, the acquisition could redefine digital sovereignty—placing personal genetic information under user control rather than corporate or governmental oversight. 

But the plan isn't without its skeptics. U.S. state attorneys general have already warned 23andMe users to delete their data, wary of how bankruptcy proceedings could expose sensitive genetic records to unexpected buyers.

How did the market react?

$SEI briefly popped 3% on the news before trimming gains, while 23andMe’s stock jumped 45%—a sharp but fragile rally for a company on the brink. 

The deal’s success depends on regulatory hurdles, creditor negotiations, and whether the public is ready for a decentralized DNA revolution.

Do you want your DNA on a blockchain?

What The Coin Is Going On? 🪙

1. Coreweave, the Nvidia-backed AI Hyperscaler, raised about $1.5B out of its mega $2.7B IPO plan. A big shot still. Reports say the stock lands on the Nasdaq today.

2. When Gary Gensler was the US SEC’s chief, almost every crypto company that mattered got either a suit or a promise of one. Crypto.com just had theirs dropped.

3. The US believes it has just dealt a blow to Hamas, the military terrorist group, by seizing about $200k worth of crypto believed to be theirs.

4. Michael Saylor’s strategy has about 500k Bitcoins. Lawmakers in the US State of Carolina want double that as a strategic investment.

5. Get clear takeaways from today’s episode on Spotify or Apple.

That’s all for this week, people.  Don’t forget to rate the newsletter

Talk Next Week,
Your Friend At Token Metrics 💛